Drug-Drug Interaction Study Evaluating Effects of ASP015K on Rosuvastatin

NCT01959399 ↗

Phase 1 Completed 24 enrolled Astellas Pharma Global Development, Inc. Janssen Biotech, Inc. · collab

NaSingle-groupOpen-label

Summary

The purpose of this study will be to assess the effect of multiple-doses of ASP015K on the pharmacokinetics of rosuvastatin in healthy adult male and female subjects.

Timeline

Start: 2013-05
Primary completion: 2013-07
Completion: 2013-07

Publications

Zhu T, Parker B, Wojtkowski T, Nishimura T, Garg JP, Han D, Fisniku O, Keirns J. Drug Interactions Between Peficitinib, an Orally Administered, Once-Daily Janus Kinase Inhibitor, and Rosuvastatin in Healthy Subjects. Clin Pharmacokinet. 2017 Jul;56(7):747-757. doi: 10.1007/s40262-016-0474-4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Rosuvastatin	Small molecule	10 mg	Oral
Subject	peficitinib	Small molecule	150 mg	Oral

Indications

No indication recorded.