drugset / Trial / NCT01960387

Phase II Clofarabine and Cytarabine for Newly Diagnosed Acute Myeloid Leukemia

NCT01960387

Phase 2 Terminated 2 enrolled University of Pittsburgh
NaSingle-groupOpen-labelTreatment

Summary

The combination of clofarabine and cytarabine is an effective and reasonably well-tolerated treatment regimen in patients with either relapsed/refractory or newly diagnosed AML. For this prospective study, we propose the use of clofarabine and cytarabine for second course induction therapy for patients with persistent AML after treatment with an anthracycline and cytarabine.

Timeline

Start
2013-10
Primary completion
2015-03
Completion
2015-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Clofarabine Other / unclassified 40 mg/m2 Intravenous
Subject Cytarabine Small molecule 1 g Intravenous