drugset / Trial / NCT01960387
Phase II Clofarabine and Cytarabine for Newly Diagnosed Acute Myeloid Leukemia
NaSingle-groupOpen-labelTreatment
Summary
The combination of clofarabine and cytarabine is an effective and reasonably well-tolerated treatment regimen in patients with either relapsed/refractory or newly diagnosed AML. For this prospective study, we propose the use of clofarabine and cytarabine for second course induction therapy for patients with persistent AML after treatment with an anthracycline and cytarabine.
Timeline
- Start
- 2013-10
- Primary completion
- 2015-03
- Completion
- 2015-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clofarabine | Other / unclassified | 40 mg/m2 | Intravenous |
| Subject | Cytarabine | Small molecule | 1 g | Intravenous |