drugset / Trial / NCT01961115
Epacadostat and Vaccine Therapy in Treating Patients With Stage III-IV Melanoma
Phase 2
Completed
11 enrolled
Fred Hutchinson Cancer Center
Incyte Corporation · collabNational Cancer Institute (NCI) · collabUniversity of Virginia · collab
NaSingle-groupOpen-labelTreatment
Summary
This pilot phase II trial studies how well epacadostat and vaccine therapy work in treating patients with stage III-IV melanoma. Epacadostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Vaccines made from peptides and antigens may help the body build an effective immune response to kill tumor cells. Giving epacadostat with vaccine therapy may be an effective treatment for advanced melanoma.
Timeline
- Start
- 2013-09-13
- Primary completion
- 2016-10-31
- Completion
- 2017-05-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Epacadostat | Small molecule | — | Oral |
| Subject | MELITAC 12.1 Peptide Vaccine | Vaccine | — | Other |