Local Anesthesia Before Arterial Puncture for Blood Gas Analysis

NCT01964248 ↗

Phase 3 Completed 136 enrolled University Hospital, Brest Ministry of Health, France · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The aim of the study is to evaluate the interest of Local Anesthesia (lidocaïne/prilocaïne versus placebo)before arterial puncture for Blood Gas Analysis. The pain is measured with a numeric Pain Intensity for all patients included.

Timeline

Start: 2012-12
Primary completion: 2015-10
Completion: 2015-10

Outcome

Missed primary endpoint

paper 95% CI when adjusting for multiple testing ranged was 0.28-1.09, P = .10; PMID 33758058 ↗

paper However, this result was not statistically significant. PMID 33758058 ↗

Publications

Beaumont M, Goret M, Orione C, Fauche A, Nowak E, Dion A, Darnois V, Tromeur C, Cogulet V, Leroyer C, Couturaud F, Le Mao R. Effect of Local Anesthesia on Pain During Arterial Puncture: The GAEL Randomized Placebo-Controlled Trial. Respir Care. 2021 Jun;66(6):976-982. doi: 10.4187/respcare.08328. Epub 2021 Mar 23.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	lidocaïne/prilocaïne	Unknown	2 g	Topical

Indications

No indication recorded.