drugset / Trial / NCT01965600
A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model
RandomizedCrossoverDouble-blindBasic science
Summary
An endotoxin challenge will be administered to healthy subjects to induce production of inflammatory markers. An investigational drug or placebo will be administered prior to the endotoxin challenge to assess the effect of the investigational drug on the markers of inflammation. Safety and tolerability will also be assessed.
Timeline
- Start
- 2014-03
- Primary completion
- 2015-02
- Completion
- 2015-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PF-06282999 | Small molecule | 125 mg | — |
| Subject | PF-06282999 | Small molecule | 500 mg | — |
Indications
No indication recorded.