drugset

drugset / Trial / NCT01974024

Dexamethasone-induced Hiccup in Chemotherapy Patients Treated by Methylprednisolone Rotation

NCT01974024 ↗

Phase 3 Completed 65 enrolled Chung-Ang University Dong-A University Hospital · collab Gyeongsang National University Hospital · collab Samsung Medical Center · collab

RandomizedCrossoverSingle-blindTreatment

Summary

The aims of this study were to investigate the feasibility of methylprednisolone rotation as treatment of DIH.

Timeline

Start: 2013-10-01
Primary completion: 2016-06-30
Completion: 2016-07-31

Publications

Go SI, Koo DH, Kim ST, Song HN, Kim RB, Jang JS, Oh SY, Lee KH, Lee SI, Kim SG, Park LC, Lee SC, Park BB, Ji JH, Yi SY, Lee YG, Yun J, Bruera E, Hwang IG, Kang JH. Antiemetic Corticosteroid Rotation from Dexamethasone to Methylprednisolone to Prevent Dexamethasone-Induced Hiccup in Cancer Patients Treated with Chemotherapy: A Randomized, Single-Blind, Crossover Phase III Trial. Oncologist. 2017 Nov;22(11):1354-1361. doi: 10.1634/theoncologist.2017-0129. Epub 2017 Jul 7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Methylprednisolone	Other / unclassified	—	—

Indications

No indication recorded.