drugset / Trial / NCT01976780
In Vivo and In Vitro Efficacy of Artemisinin Combination Therapy
Phase 4
Completed
118 enrolled
Global Emerging Infections Surveillance and Response System
United States Army Medical Unit - Kenya · collabWalter Reed Army Institute of Research (WRAIR) · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This study aims to assess the degree of artemisinin resistance in adult and pediatric subjects presenting with uncomplicated falciparum malaria in Western Kenya. The study treatments will be Artemether Lumefantrine (AL) and Artesunate Mefloquine (ASMQ).
Timeline
- Start
- 2013-06
- Primary completion
- 2014-12
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Artemether-lumefantrine | Unknown | — | — |
| Comparator | Artesunate | Small molecule | 4 mg/kg | — |
| Comparator | Mefloquine | Unknown | 25 mg/kg | — |