drugset

drugset / Trial / NCT01978431

Impulsivity and Stimulant Administration

NCT01978431 ↗

Phase 1 Completed 29 enrolled Yale University National Institute of Mental Health (NIMH) · collab

RandomizedFactorialQuadruple-blindBasic science

Summary

Examine the interaction between stimulants, such as cocaine and methylphenidate, and impulsivity.

Timeline

Start: 2012-11
Primary completion: 2014-05
Completion: 2014-05

Publications

Kohler RJ, Zhornitsky S, Potenza MN, Yip SW, Worhunsky P, Angarita GA. Cocaine self-administration behavior is associated with subcortical and cortical morphometry measures in individuals with cocaine use disorder. Am J Drug Alcohol Abuse. 2024 May 3;50(3):345-356. doi: 10.1080/00952990.2024.2318585. Epub 2024 Mar 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cocaine	Small molecule	0.114286 mg/kg	—
Subject	Cocaine	Small molecule	0.228571 mg/kg	—
Subject	Cocaine	Small molecule	0.457143 mg/kg	—
Subject	Methylphenidate	Small molecule	—	—

Indications