drugset / Trial / NCT01978457

Establishing and Eliminating Cue-drug Associations in Human Cocaine Addiction

NCT01978457

Phase 1 Terminated 6 enrolled Yale University
RandomizedSingle-groupQuadruple-blindBasic science

Summary

We will develop a procedure for conditioning cue-cocaine associations in human drug users. Next, we will reactivate that learning and intervene pharmacologically to prevent the reconsolidation of cue-drug memories. We hypothesize that a combined behavioral and pharmacological approach will have significant potential for persistently inhibiting relapse.

Timeline

Start
2012-10
Primary completion
2019-12
Completion
2019-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cocaine Small molecule
Subject Propranolol Small molecule

Indications