drugset / Trial / NCT01981187

LGX818 for Patients With BRAFV600 Mutated Tumors

NCT01981187 ↗

Phase 2 Terminated 12 enrolled Pfizer
NaSingle-groupTreatment

Summary

The purpose of this signal seeking study is to determine whether treatment with LGX818 demonstrates sufficient efficacy in select pathway-activated solid tumors and/or hematologic malignancies to warrant further study

Timeline

Start
2014-01-14
Primary completion
2015-09-01
Completion
2015-10-13

Outcome

Outcome not reported

Stopped (Enrollment): “Due to slow enrollment and lack of response observed during the enrollment period, the Sponsor decided to close study enrollment early on 28 January 2015”

Drugs

EvaluationDrugModalityDoseRoute
Subject Encorafenib Small molecule 300 mg —