drugset / Trial / NCT01981395

Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers

NCT01981395 ↗

Phase 1 Completed 33 enrolled Laura Cavallone
RandomizedCrossoverDouble-blind

Summary

Our goal is to demonstrate that healthy volunteers treated with fenobam will develop a significantly reduced area of cutaneous hyperalgesia compared to volunteers treated with placebo, after exposure to the heat/capsaicin model of cutaneous sensitization. Additionally we are going to assess changes in mood/affect and cognitive function of subjects following administration of fenobam and after cutaneous sensitization compared to baseline.

Timeline

Start
2014-01
Primary completion
2015-02
Completion
2016-04

Drugs

EvaluationDrugModalityDoseRoute
Subject FENOBAM ANHYDROUS Small molecule 150 mg Oral

Indications