drugset / Trial / NCT01988077
Clinical Evaluation of Yervoy in Combination With Adoptive T Cell Transfer for Metastatic Melanoma Patients
NaSingle-groupOpen-labelTreatment
Summary
A rationally designed combination of adoptive T cell therapy and ipilimumab could strongly increase the proportion of CR patients, as well as the durability of response, as compared to ipilimumab or TIL alone. The investigators hypothesize that the combination of those two important modalities could result in a durable (≥ 1 year) complete response rate of 30% in stage IV melanoma patients.
Timeline
- Start
- 2013-10
- Primary completion
- 2016-05-20
- Completion
- 2018-10-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ipilimumab | Monoclonal antibody | 5 mg/ml | — |
| Subject | T-Cell Therapy | Cell therapy | — | — |
Indications
No indication recorded.