drugset / Trial / NCT01988883
Modafinil and Cognitive Function in POTS
Phase 0
Active not recruiting
20 enrolled
Vanderbilt University Medical Center
National Center for Advancing Translational Sciences (NCATS) · collab
RandomizedCrossoverTriple-blindTreatment
Summary
A common complaint among patients with Postural Tachycardia Syndrome (POTS) is "brain fog" or difficulty concentrating. This problem is poorly understood. The purpose of this study is to better understand the cognitive dysfunction associated POTS, and to determine optimal treatment strategies for this condition. In this study, the investigators will test the hypothesis that acute administration of the psychostimulant drug modafinil can improve seated measures of cognitive function in patients with POTS.
Timeline
- Start
- 2014-10
- Primary completion
- 2026-12
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Modafinil | Small molecule | 200 mg | Oral |
| Subject | Propranolol | Small molecule | 20 mg | Oral |