drugset / Trial / NCT01989455
A Blinded, Placebo-Controlled Study of the Safety and Pharmacokinetics of Single Doses of Intravenous Deferiprone in Healthy Volunteers
RandomizedParallel-groupQuadruple-blind
Summary
Single center, randomized, double-blind, placebo-controlled, adaptive sequential ascending-dose study for the evaluation of the safety, tolerability, and pharmacokinetics of single doses of deferiprone administered by intravenous infusion to healthy males and females. A bioavailability comparison will be included.
Timeline
- Start
- 2013-11
- Primary completion
- 2014-03
- Completion
- 2014-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Deferiprone | Small molecule | 500 mg | Intravenous |
| Subject | Deferiprone | Small molecule | 1000 mg | Intravenous |
| Subject | Deferiprone | Small molecule | 1500 mg | Intravenous |
| Subject | Deferiprone | Small molecule | 2000 mg | Intravenous |
Indications
No indication recorded.