drugset / Trial / NCT01989598

Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT01989598

Phase 2 Completed 25 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well trametinib and Akt inhibitor GSK2141795 work in treating patients with multiple myeloma that has come back (relapsed) or that does not respond to treatment (refractory). Trametinib and Akt inhibitor GSK2141795 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2013-10-30
Primary completion
2019-08-31
Completion
2020-09-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Trametinib Small molecule Oral
Subject Uprosertib Small molecule Oral

Indications