drugset / Trial / NCT01992198
Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis
RandomizedCrossoverOpen-labelTreatment
Summary
Strategy of antibiotic therapy in SAP,De-escalate (cefoperazone+metronidazole) or Escalate (meropenem) therapy,which one is better.
Timeline
- Start
- 2012-07
- Primary completion
- 2015-12
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cefoperazone | Small molecule | 2 g | — |
| Subject | Meropenem | Small molecule | 0.5 g | — |
| Comparator | Metronidazole | Small molecule | 0.5 g | — |
| Background | Somatostatin | Traditional medicine (herbal / TCM) | — | — |