drugset / Trial / NCT01992796

Angiotensin II Antagonist in Severe Sepsis

NCT01992796

RandomizedParallel-groupTriple-blindTreatment

Summary

The investigators propose a clinical study of irbersartan for the early treatment of severe sepsis patients with elevated predicted risk of death between. This study will evaluate whether early administration of the the angiotensin receptor blocker irbersartan provides significant reduction of 28 days mortality and multi organ failure incidence to patients with severe sepsis.

Timeline

Start
2014-01
Primary completion
2017-01
Completion
2017-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Irbesartan Small molecule 75 mg Oral