Does Duloxetine Reduce Sub-Acute Pain After Knee Arthroplasty?

Summary

We are investigating the impact of duloxetine ("Cymbalta"), a serotonin and norepinephrine reuptake inhibitor, on pain after total knee arthroplasty (TKA). Specifically, the investigators will determine whether duloxetine, 60 mg daily for 2 weeks, reduces pain scores 2 weeks after TKA.

Timeline

Start

2013-11

Primary completion

2015-05

Completion

2015-08

Drugs

Indications

No indication recorded.