Imaging Kidney Transplant Rejection Using Ferumoxytol-Enhanced Magnetic Resonance

Summary

The goal of this study is to develop a non-invasive imaging test for in vivo detection of kidney transplant rejection. The hypotheses are that 1) Ferumoxytol-MRI can generate accurate estimates of tissue iron concentrations and tissue macrophages. 2) The signal given by a renal allograft on Ferumoxytol-MRI demonstrates significant differences between rejected and non-rejected transplants.

Timeline

Start

2012-11-27

Primary completion

2017-04-11

Completion

2017-04-11

Drugs

Indications