drugset / Trial / NCT02008786

Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD

NCT02008786

Phase 4 Terminated 18 enrolled Cardiology Research UBC
RandomizedCrossoverQuadruple-blindTreatment

Summary

An emerging cause of heart attack in young women is a dissection (or tear) in the coronary arteries. Many of these young women continue to have chest pain long after the tear has healed and this is thought to be due to problems with their small blood vessels of the heart (or microcirculation). We want to determine whether commonly used medications for coronary artery disease including statins (for cholesterol) and angiotensin-converting enzyme inhibitors (for blood pressure) reduce chest pain and improve small vessel function in these patients.

Timeline

Start
2014-06
Primary completion
2019-09-13
Completion
2019-09-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Ramipril Small molecule 10 mg
Subject Rosuvastatin Small molecule 10 mg
Subject Rosuvastatin Small molecule 20 mg