drugset / Trial / NCT02009878
A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
RandomizedParallel-groupTriple-blindBasic science
Summary
This is a study to evaluate how the body handles and metabolizes (PK) the various doses of the drug Tolvaptan, and what the effect (PD) of the various doses of Tolvaptan are on the content of "salt" in blood and urine
Timeline
- Start
- 2013-11
- Primary completion
- 2015-06
- Completion
- 2015-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tolvaptan | Small molecule | 3.75 mg | Oral |
| Subject | Tolvaptan | Small molecule | 7.5 mg | Oral |
| Subject | Tolvaptan | Small molecule | 15 mg | Oral |