The Effect of Sponge Versus No-Sponge Placement of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS Glaucoma Filtration Device

Summary

The primary focus of this study is to assess intraocular pressure and complication rates between patients who receive mitomycin-C using a sponge versus no-sponge.

Timeline

Start

2014-03

Primary completion

2017-01-17

Completion

2017-01-17

Outcome

Missed primary endpoint

registry analysis (other test); Sponge Placement of Mitomycin-C vs Irrigation Placement of MMC; p = 0.7; Risk Ratio (RR) 0.93 (95% CI 0.67 to 1.29); Chi-squared NCT02016898 ↗

Publications

• Quist MS, Brown N, Bicket AK, Herndon LW. The Short-term Effect of Subtenon Sponge Application Versus Subtenon Irrigation of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS Glaucoma Filtration Device: A Randomized Trial. J Glaucoma. 2018 Feb;27(2):148-156. doi: 10.1097/IJG.0000000000000830.

Drugs

Indications