drugset / Trial / NCT02022592

Comparison of Lormetazepam and Midazolam Used as Sedatives for Patients That Require Intensive Care

NCT02022592

Phase 4 Completed 84 enrolled Claudia Spies
RandomizedParallel-groupQuadruple-blindTreatment

Summary

A goal directed , demand-driven administration of sedative drugs is an integral part of every intensive care treatment. During long-term application of sedatives, Midazolam is the most commonly used sedative in Europe. One major objective is the problem of oversedation and agitation during an intensive care treatment due to the lack of controllability of available substances. The Love-Mi RCT investigates the clinical controllability of Midazolam versus the newly available intravenous drug Lormetazepam.

Timeline

Start
2014-07-17
Primary completion
2019-12-12
Completion
2020-03-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Lormetazepam Small molecule Intravenous
Comparator Midazolam Small molecule

Indications

No indication recorded.