drugset / Trial / NCT02022670
Sodium Nitrite to Treat Arterial Aging
RandomizedParallel-groupTriple-blindTreatment
Summary
The proposed research will determine the effectiveness of nitrite, a naturally occurring compound in the body, for improving the health and function of arteries in middle-aged and older adults. The study also will provide insight into how sodium nitrite therapy improves artery health by determining the physiological mechanisms (biological reasons) involved. Overall, the proposed research will provide important new scientific evidence on the effectiveness of sodium nitrite for decreasing the risk of developing cardiovascular diseases with aging.
Timeline
- Start
- 2011-10
- Primary completion
- 2013-12
- Completion
- 2013-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sodium Nitrite | Small molecule | 80 mg | Oral |
| Subject | Sodium Nitrite | Small molecule | 160 mg | Oral |