drugset / Trial / NCT02022670

Sodium Nitrite to Treat Arterial Aging

NCT02022670

RandomizedParallel-groupTriple-blindTreatment

Summary

The proposed research will determine the effectiveness of nitrite, a naturally occurring compound in the body, for improving the health and function of arteries in middle-aged and older adults. The study also will provide insight into how sodium nitrite therapy improves artery health by determining the physiological mechanisms (biological reasons) involved. Overall, the proposed research will provide important new scientific evidence on the effectiveness of sodium nitrite for decreasing the risk of developing cardiovascular diseases with aging.

Timeline

Start
2011-10
Primary completion
2013-12
Completion
2013-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Sodium Nitrite Small molecule 80 mg Oral
Subject Sodium Nitrite Small molecule 160 mg Oral

Indications