drugset / Trial / NCT02022982

PALBOCICLIB + PD-0325901 for NSCLC & Solid Tumors

NCT02022982

Phase 1 Completed 60 enrolled Dana-Farber Cancer Institute
NaSingle-groupOpen-labelTreatment

Summary

This research study is evaluating the experimental drug palbociclib in combination with another experimental drug PD-0325901 as a possible treatment for cancers with KRAS mutations, particularly for those which started in the lung.

Timeline

Start
2014-01
Primary completion
2017-11-01
Completion
2021-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Mirdametinib Small molecule 2 mg Oral
Subject Palbociclib Small molecule 75 mg Oral

Indications