Selumetinib in Combination With Gefitinib in NSCLC Patients

Summary

This is an open-label, non-randomized, multicenter phase Ib/II study, which is composed of a phase Ib dose escalation part and a phase II dose expansion part. Patients will receive selumetinib in combination with gefitinib 250mg daily. This study will enroll EGFR-mutated NSCLC patients who have developed acquired resistance to EGFR TKI treatment.

Timeline

Start

2014-09

Primary completion

2018-03-08

Completion

2018-03-08

Drugs

Indications