drugset / Trial / NCT02026401
Phase 2 Study of NGM282 in Patients With Primary Biliary Cirrhosis
Phase 2
Completed
45 enrolled
NGM Biopharmaceuticals, Inc
NGM Biopharmaceuticals Australia Pty Ltd · collab
RandomizedFactorialDouble-blindTreatment
Summary
The purpose of this study is to determine the safety, tolerability, and activity of NGM282 in patients with Primary Biliary Cirrhosis.
Timeline
- Start
- 2014-02
- Primary completion
- 2014-12
- Completion
- 2014-12
Outcome
Met primary endpoint
release “Data from the trial demonstrated a statistically significant and clinically meaningful percentage reduction in ALP from baseline to day 28 in both NGM282 treatment arms” ngmbio.com ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aldafermin | Protein / enzyme biologic | — | — |