Cabozantinib in Recurrent/Metastatic Merkel Cell Carcinoma

Summary

This is an open-label, non-randomized, phase 2 study to assess the feasibility of using cabozantinib in recurrent/metastatic Merkel Cell Carcinoma patients that progressed after platinum-based therapy.

Timeline

Start

2014-02

Primary completion

2016-04

Completion

2016-07

Outcome

Outcome not reported

Stopped (Enrollment): “Lack of accrual.”

Publications

• Results Rabinowits G, Lezcano C, Catalano PJ, McHugh P, Becker H, Reilly MM, Huang J, Tyagi A, Thakuria M, Bresler SC, Sholl LM, Shapiro GI, Haddad R, DeCaprio JA. Cabozantinib in Patients with Advanced Merkel Cell Carcinoma. Oncologist. 2018 Jul;23(7):814-821. doi: 10.1634/theoncologist.2017-0552. Epub 2018 Feb 14.

Drugs

Indications