drugset / Trial / NCT02036645

SAD/MAD Study to Assess Safety, Tolerability, PK & PD of MEDI1814 in Subjects With Mild-Moderate Alzheimer's Disease.

NCT02036645 ↗

Phase 1 Completed 77 enrolled AstraZeneca
RandomizedParallel-groupTriple-blindBasic science

Summary

The purpose of this study is to assess the safety, drug levels and effects on the body of 1 or 3 injections of MEDI1814, in people with mild to moderate Alzhiemer's Disease or healthy elderly people.

Timeline

Start
2014-02-04
Primary completion
2016-09-15
Completion
2016-09-15

Drugs

EvaluationDrugModalityDoseRoute
Subject MEDI1814 Monoclonal antibody 25 mg Intravenous
Subject MEDI1814 Monoclonal antibody 1800 mg Intravenous

Indications