drugset / Trial / NCT02037477
Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of Vonoprazan (TAK-438)
RandomizedCrossoverOpen-labelTreatment
Summary
The purpose of this study is to investigate the acid-inhibitory effect of multiple oral doses of Vonoprazan (TAK-438) and the relative effect of vonoprazan versus two controls (esomeprazole and rabeprazole sodium) in healthy Japanese adult male participants with the CYP2C19 extensive metabolizer (EM) genotype.
Timeline
- Start
- 2014-01
- Primary completion
- 2014-03
- Completion
- 2014-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esomeprazole | Small molecule | 20 mg | Oral |
| Subject | Rabeprazole | Small molecule | 10 mg | Oral |
| Subject | Vonoprazan | Other / unclassified | 20 mg | Oral |
Indications
No indication recorded.