drugset / Trial / NCT02044653

Study to Evaluate the Efficacy and Safety of GX-E2 in the Anemic Patients Diagnosed With Chronic Kidney Disease (CKD)

NCT02044653

Phase 2 Completed 257 enrolled Genexine, Inc.
RandomizedParallel-groupSingle-blindTreatment

Summary

The primary objective of study is * Part A : To explore the optimal fixed starting dose and dosing interval of GX-E2 * Part B : To evaluate the proof of concept (POC) of GX-E2

Timeline

Start
2014-04-15
Primary completion
2017-04-20
Completion
2017-04-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Darbepoetin alfa Protein / enzyme biologic 30 ug Intravenous
Subject GX-E2 Unknown 3 ug/kg Subcutaneous
Subject GX-E2 Unknown 5 ug/kg Subcutaneous
Subject GX-E2 Unknown 8 ug/kg Subcutaneous
Comparator methoxy polyethylene glycol-epoetin beta Protein / enzyme biologic 0.6 ug/kg Subcutaneous