drugset / Trial / NCT02048423

An Open Prospective Trial of IV Ketamine in Suicidal Adolescents

NCT02048423

Phase 2/3 Unknown 10 enrolled Nationwide Children's Hospital
NaSingle-groupOpen-labelTreatment

Summary

1. Investigate the safety and effectiveness of a single dose of IV Ketamine for adolescents with suicidal ideation and depression. It is hypothesize that Ketamine will be well tolerated and significantly reduce depressive symptoms and suicidal ideation. 2. Explore whether decision making as measured by the Iowa Gambling Task changes before and after Ketamine infusion. It is hypothesize that IV Ketamine infusion will significantly improve the decision making ability a measured by the Iowa Gambling Task in adolescents that are suicidal.

Timeline

Start
2013-06
Primary completion
2015-06
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.5 mg/kg Intravenous