A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LFX453

Summary

The purpose of this first-in human study is to demonstrate systemic and local tolerability and investigate pharmacokinetics of LFX453 after multiple topical applications in healthy subjects. The current study has been designed with three distinct parts. Part 1 focuses on safety and tolerability of once daily application on the back, prior to moving forward and assessing the safety and tolerability in more sensitive treatment areas in Part 2 or twice daily application in Part 3.

Timeline

Start

2014-01

Primary completion

2014-06

Completion

2014-06

Drugs

Indications

No indication recorded.