Effects of Local Anesthesia on Post-operative Pain During Laparoscopic Inguinal Hernia Repair

NCT02055053 ↗

Phase 4 Completed 70 enrolled Lahey Clinic

RandomizedParallel-groupDouble-blindTreatment

Summary

To assess effect of local anesthetic into the preperitoneal space during laparoscopic hernia repair on post-operative pain.

Timeline

Start: 2013-08
Primary completion: 2019-10-16
Completion: 2019-10-16

Outcome

Missed primary endpoint

paper No differences were found in post-operative pain between the control and test groups at 1 h [mean (SD) of 3.15(2.5) vs 3.21(2.9); P = 0.92] PMID 36266481 ↗

paper Instilling local anesthetic into the preperitoneal space during laparoscopic TEP inguinal hernia repair did not result in statistically significant difference in post-operative pain PMID 36266481 ↗

Publications

Rade M, Jayaram A, Birkett R, Ford H, Birkett D, Nepomnayshy D. A randomized, double-blinded, placebo-controlled trial of the effects of infusing local analgesia on post-operative pain during laparoscopic inguinal hernia repair. Surg Endosc. 2023 Mar;37(3):1970-1975. doi: 10.1007/s00464-022-09697-7. Epub 2022 Oct 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Bupivicaine	Other / unclassified	0.5 %	Other

Indications

No indication recorded.