drugset

drugset / Trial / NCT02056665

Study to Evaluate the Efficacy and Safety of Minocycline in Angelman Syndrome

NCT02056665 ↗

Phase 2 Completed 32 enrolled Puerta de Hierro University Hospital

RandomizedCrossoverQuadruple-blindTreatment

Summary

RANDOMIZED CLINICAL TRIAL, PLACEBO COMPARED TO EVALUATE THE EFFICACY AND SAFETY OF MINOCYCLINE IN ANGELMAN SYNDROME (A-MANECE STUDY)

Timeline

Start: 2014-01
Primary completion: 2014-09
Completion: 2014-11

Publications

Ruiz-Antoran B, Sancho-Lopez A, Cazorla-Calleja R, Lopez-Pajaro LF, Leiva A, Iglesias-Escalera G, Marin-Serrano ME, Rincon-Ortega M, Lara-Herguedas J, Rossignoli-Palomeque T, Valiente-Rodriguez S, Gonzalez-Marques J, Roman-Riechmann E, Avendano-Sola C. A randomized placebo controlled clinical trial to evaluate the efficacy and safety of minocycline in patients with Angelman syndrome (A-MANECE study). Orphanet J Rare Dis. 2018 Aug 20;13(1):144. doi: 10.1186/s13023-018-0891-6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Minocycline	Small molecule	100 mg	Oral
Subject	Minocycline	Small molecule	150 mg	Oral
Subject	Minocycline	Small molecule	200 mg	Oral

Indications