drugset / Trial / NCT02057211

Mesenchymal Stem Cells to Intervene in the Development of Type 1 Diabetes: a Blinded Randomized Study

NCT02057211

Phase 2 Terminated 10 enrolled Uppsala University Hospital
RandomizedParallel-groupTriple-blindPrevention

Summary

This project aims to evaluate the efficacy of autologous mesenchymal stem cell treatment to preserve insulin production and beta-cell mass in recently diagnosed patients with type 1 diabetes mellitus. The hypothesis to be tested is that an increased number of circulating mesenchymal stem cells will provide immune modulatory properties, and thereby stop the immune process in islets causing progressive beta-cell death.

Timeline

Start
2014-04
Primary completion
2017-11
Completion
2017-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator mesenchymal stem cells Cell therapy