Hematopoietic Stem Cell Transplant for Sickle Cell Disease

Summary

This is a study of patients with sickle cell disease. It aims to find out if people with sickle cell disease can be cured by changing their immune system before they have blood stem cell transplants. Doctors will give patients a new drug (fludarabine) to see if this drug changes patients immune system and reduces the patient's cells (host) from rejecting donor cells (graft) after the patient gets a Hematopoietic (blood) stem cell transplant.

Timeline

Start

2015-10-19

Primary completion

2023-02-17

Completion

2023-02-17

Drugs

Indications