drugset / Trial / NCT02068235
Study to Investigate the Absolute Bioavailability of a Single Oral Dose of Ponesimod in Healthy Male Subjects
RandomizedCrossoverOpen-label
Summary
This study consists of a single-dose pilot phase and a randomized, two-way crossover, single-dose main phase.The aim of this study is to evaluate the absolute bioavailability of the oral formulation (tablet) of ponesimod compared to an intravenous (i.v.) ponesimod formulation. Three subjects will be included in the pilot phase and 12 subjects in the main crossover phase.
Timeline
- Start
- 2014-08
- Primary completion
- 2014-11
- Completion
- 2014-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ponesimod | Small molecule | 5 mg | Intravenous |
| Subject | Ponesimod | Small molecule | 10 mg | Intravenous |
Indications
No indication recorded.