drugset / Trial / NCT02069119
A Trial to Determine the Safety, Pharmacokinetics, and Efficacy of OPC-108459 Administered as a Single Intravenous Dose to Patients With Paroxysmal or Persistent Atrial Fibrillation (AF)
RandomizedParallel-groupQuadruple-blindTreatment
Summary
To investigate the safety, pharmacokinetics, and efficacy following 30-minute continuous intravenous administration of OPC-108459 at 0.4, 0.8, 1.6, or 2.4 mg/kg or placebo to patients with paroxysmal or persistent atrial fibrillation
Timeline
- Start
- 2014-02
- Primary completion
- 2015-08
- Completion
- 2015-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | OPC-108459 | Unknown | 0.4 mg/kg | Intravenous |
| Subject | OPC-108459 | Unknown | 0.8 mg/kg | Intravenous |
| Subject | OPC-108459 | Unknown | 1.6 mg/kg | Intravenous |
| Subject | OPC-108459 | Unknown | 2.4 mg/kg | Intravenous |