Efficacy of Oxytocin vs. Carbetocin in Prevention of Postpartum Hemorrhage After Cesarean Section

NCT02079558 ↗

Phase 2 Completed 220 enrolled Shahid Beheshti University of Medical Sciences

RandomizedParallel-groupDouble-blindScreening

Summary

Postpartum hemorrhage (PPH) is a common complication of childbirth and a leading cause of maternal morbidity and mortality. The prompt and effective treatment of subjects with PPH would reduce operation risks. Hence in this study, the efficacy of Oxytocin and Carbetocin was compared in prevention of postpartum hemorrhage after cesarean sections.

Timeline

Start: 2012-09
Primary completion: 2013-09
Completion: 2013-09

Publications

Taheripanah R, Shoman A, Karimzadeh MA, Zamaniyan M, Malih N. Efficacy of oxytocin versus carbetocin in prevention of postpartum hemorrhage after cesarean section under general anesthesia: a prospective randomized clinical trial. J Matern Fetal Neonatal Med. 2018 Nov;31(21):2807-2812. doi: 10.1080/14767058.2017.1355907. Epub 2017 Jul 25.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Carbetocin	Peptide	100 ug	Intravenous
Subject	Oxytocin	Peptide	30 iu	Intravenous

Indications

No indication recorded.