drugset / Trial / NCT02080715
Role of the Catechol-O-methyltransferase (COMT) in the Physiological Regulation of Vigilance
NaSingle-groupDouble-blindTreatment
Summary
In this study, pharmacologic effects of COMT inhibition during sleep deprivation in healthy subjects in dependence of their Val158Met genotype of COMT are studied. Potential effects are identified by measurement of vigilance and cognitive performance as well as EEG measurements during wake and sleep. * Trial with medicinal product
Timeline
- Start
- 2013-06
- Primary completion
- 2014-04
- Completion
- 2014-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tolcapone | Unknown | 100 mg | — |
Indications
No indication recorded.