drugset / Trial / NCT02087332
Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics.
RandomizedParallel-groupOpen-labelTreatment
Summary
Study hypothesis is that the time from randomization to the increase of natriuresis (%), time to standardization of natriuresis daily profile, blood pressure profile and the percentage reduction of central hemodynamic parameters will be relatively changed over the study period by more than 15%.
Timeline
- Start
- 2014-04
- Primary completion
- 2015-05
- Completion
- 2015-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Torasemide | Unknown | 5 mg | Oral |
| Subject | Torasemide | Unknown | 10 mg | Oral |
| Subject | Torasemide | Unknown | 20 mg | Oral |
| Subject | Torasemide | Unknown | 40 mg | Oral |