drugset / Trial / NCT02087579
Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric Participants
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The purpose of this study is to gather information about the steady-state plasma concentrations of aripiprazole, olanzapine, quetiapine and their relevant metabolites, at various dose levels and at different time points after dosing. In addition, comparison of capillary drug concentrations vs. venous drug concentrations will be performed for aripiprazole, olanzapine, paliperidone, quetiapine, risperidone and their relevant metabolites.
Timeline
- Start
- 2014-02
- Primary completion
- 2014-10
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aripiprazole | Other / unclassified | — | Oral |
| Subject | Olanzapine | Small molecule | — | Oral |
| Subject | Paliperidone | Unknown | — | Oral |
| Subject | Paliperidone | Unknown | — | Other |
| Subject | Quetiapine | Small molecule | — | Oral |
| Subject | Risperidone | Other / unclassified | — | Oral |
| Subject | Risperidone | Other / unclassified | — | Other |