drugset / Trial / NCT02089438
DPP-4 Inhibition, Incretins and Islet Function
RandomizedParallel-groupOpen-labelBasic science
Summary
Hypothesis is that DPP-4 inhibition affects glucose levels through changes in incretin and islet hormones. The study examines this in relation to breakfast, lunch and dinner over an entire 24h study period by the use of three different DPP-4 inhibitors and placebo.
Timeline
- Start
- 2014-05
- Primary completion
- 2017-06
- Completion
- 2017-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | SAXAGLIPTIN ANHYDROUS | Small molecule | 5 mg | — |
| Subject | Sitagliptin | Small molecule | 100 mg | — |
| Subject | Vildagliptin | Other / unclassified | 50 mg | — |