drugset / Trial / NCT02090244

Does PTH 1-34 (Teriparatide) Enhance Spinal Fusion in Humans?

NCT02090244

RandomizedParallel-groupSingle-blindTreatment

Summary

Parathyroid (PTH) hormone has been shown to enhance fracture healing in animal studies. There are so far only three published papers concerning humans. Postero-lateral fusions have shown a healing rate of less than 50% after bone. The purpose of this study is to determine if PTH 1-34 (teriparatide) improves the healing rate and the clinical course after spinal stenosis surgery.

Timeline

Start
2012-08
Primary completion
2018-05
Completion
2019-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Teriparatide Protein / enzyme biologic 20 ug

Indications