drugset / Trial / NCT02090244
Does PTH 1-34 (Teriparatide) Enhance Spinal Fusion in Humans?
Phase 4
Completed
34 enrolled
University Hospital, Linkoeping
Medical Research Council of Southeast Sweden · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
Parathyroid (PTH) hormone has been shown to enhance fracture healing in animal studies. There are so far only three published papers concerning humans. Postero-lateral fusions have shown a healing rate of less than 50% after bone. The purpose of this study is to determine if PTH 1-34 (teriparatide) improves the healing rate and the clinical course after spinal stenosis surgery.
Timeline
- Start
- 2012-08
- Primary completion
- 2018-05
- Completion
- 2019-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Teriparatide | Protein / enzyme biologic | 20 ug | — |