drugset / Trial / NCT02093728
To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
RandomizedParallel-groupOpen-labelBasic science
Summary
Study to assess the effect of Itraconazole and Fluconazole on the pharmacokinetics of Selumetinib (AZD6244; ARRY-142866) ( Hyd-Sulfate) in Healthy Male Volunteers
Timeline
- Start
- 2014-04
- Primary completion
- 2014-06
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluconazole | Small molecule | 200 mg | Oral |
| Subject | Itraconazole | Small molecule | 200 mg | Oral |
| Subject | Selumetinib | Small molecule | 25 mg | Oral |