Intra-arterial Melphalan in Treating Younger Patients With Unilateral Retinoblastoma

Summary

This pilot clinical trial studies whether unilateral group D retinoblastoma, or retinoblastoma affecting one eye that has spread to the inner jelly like part of the eye, can be treated with a new technique for delivering chemotherapy directly into the blood vessel that supplies the affected eye. This new technique is called intra-arterial injection. Giving melphalan via intra-arterial injection may make it less likely that children will need surgery to remove the eye and may reduce the amount of treatment side effects.

Timeline

Start

2014-10-31

Primary completion

2017-06-30

Completion

2023-09-30

Drugs

Indications