drugset / Trial / NCT02097329
Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And Food
Non-randomizedParallel-groupOpen-labelBasic science
Summary
To investigate the effect of acid reducing agents (an antacid and an H2-receptor antagonist and a proton pump inhibitor) on palbociclib bioavailability in the presence of food.
Timeline
- Start
- 2014-04
- Primary completion
- 2014-06
- Completion
- 2014-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Famotidine | Other / unclassified | 20 mg | Oral |
| Subject | Maalox | Unknown | 30 ml | Oral |
| Subject | Palbociclib | Small molecule | 125 mg | Oral |
| Subject | Rabeprazole | Small molecule | 40 mg | Oral |
Indications
No indication recorded.