drugset / Trial / NCT02097459
Prognostic Evaluation of Changing Endocrine Therapy in Women With Breast Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
It suggests in the Guideline that the postmenopausal women with breast cancer who have taken selective estrogen receptor modulators (SERMs) therapy for 2-3 years could benefit from changing endocrine therapy to aromatase inhibitors (AIs). This is a prospective, randomized and non-inferior trial to evaluate the prognosis of changing endocrine therapy from SERMs to AIs in perimenopausal and recently postmenopausal women with early-stage hormone receptor-positive breast cancer.
Timeline
- Start
- 2014-03
- Primary completion
- 2024-03
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Anastrozole | Other / unclassified | — | — |
| Subject | Tamoxifen | Small molecule | — | — |
| Subject | Toremifene | Small molecule | — | — |