drugset / Trial / NCT02097459

Prognostic Evaluation of Changing Endocrine Therapy in Women With Breast Cancer

NCT02097459

Phase 3 Unknown 600 enrolled Peking Union Medical College Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

It suggests in the Guideline that the postmenopausal women with breast cancer who have taken selective estrogen receptor modulators (SERMs) therapy for 2-3 years could benefit from changing endocrine therapy to aromatase inhibitors (AIs). This is a prospective, randomized and non-inferior trial to evaluate the prognosis of changing endocrine therapy from SERMs to AIs in perimenopausal and recently postmenopausal women with early-stage hormone receptor-positive breast cancer.

Timeline

Start
2014-03
Primary completion
2024-03
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Anastrozole Other / unclassified
Subject Tamoxifen Small molecule
Subject Toremifene Small molecule

Indications