drugset / Trial / NCT02097732

Ipilimumab Induction in Patients With Melanoma Brain Metastases Receiving Stereotactic Radiosurgery

NCT02097732 ↗

Phase 2 Terminated 4 enrolled University of Michigan Rogel Cancer Center
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a study to test the efficacy of using standard immune therapy for melanoma prior to stereotactic radiosurgery (ipilimumab induction), as compared to stereotactic radiosurgery followed by immune therapy. The study's hypothesis is that ipilimumab induction is as good as or better than controlling brain metastases as compared to stereotactic radiosurgery followed by immune therapy.

Timeline

Start
2014-04
Primary completion
2016-08
Completion
2020-07

Outcome

Outcome not reported

Stopped: “Study halted prematurely due to a change in the standard of care treatment”

Drugs

EvaluationDrugModalityDoseRoute
Subject Ipilimumab Monoclonal antibody 3 mg/kg Intravenous